Publications (peer-reviewed)

2020

McCollum C, Engelhardt S, Weiss L, Hückelhoven R (2020) ROP INTERACTIVE PARTNER b interacts with RACB and supports fungal penetration into barley epidermal cells. Plant Physiol.
doi: https://doi.org/10.1104/pp.20.00742

Dunker F, Trutzenberg A, Rothenpieler JS, Kuhn S, Pröls R, Schreiber T, Tissier A, Kemen A, Kemen E, Hückelhoven R, Weiberg A (2020) Oomycete small RNAs bind to the plant RNA-induced silencing complex for virulence. elife 9:e56096 doi: 10.7554/eLife.56096

Hoefle C, McCollum C, Hückelhoven R (2020) Barley ROP-Interactive Partner-a organizes into RAC1- and MICROTUBULE-ASSOCIATED ROP-GTPASE ACTIVATING PROTEIN 1-dependent membrane domains. BMC Plant Biol 20, 94

2019

Stam R, Nosenko T, Hörger AC, Stephan W, Seidel M, Kuhn JMM, Haberer G, Tellier A (2019) The de novo reference genome and transcriptome assemblies of the wild tomato species Solanum chilense highlights birth and death of NLR Genes between tomato species. G3 9: 3933-3941.

Kutschera A, Schombel U, Wröbel M, Gisch N, Ranf S (2019) Loss of wbpL disrupts O-polysaccharide synthesis and impairs virulence of plant-associated Pseudomonas strains. Mol Plant Pathol. 20: 1535-1549. doi: 10.1111/mpp.12864

Mucha S, Heinzlmeir S, Kriechbaumer V, Strickland B, Kirchhelle C, Choudhary M, Kowalski N, Eichmann R, Hückelhoven R, Grill E, Kuster B, Glawischnig E (2019) The formation of a camalexin-biosynthetic metabolon. Plant Cell 31: 2697-2710 

Matušinsky P, Svobodová LL, Svacinová I, Havis N, Hess M, Tvaružek L (2019) Population genetic structure of Microdochium majus and Microdochium nivale associated with foot rot of cereals in the Czech Republic and adaptation to penthiopyrad. Eur. J. Plant Pathol. 155:1-12

Stam R,Sghyer H, Tellier A, Hess M, Hückelhoven R (2019) The current epidemic of the barley pathogen Ramularia collo-cygni derives from a recent population expansion and shows global admixture. Phytopathol. 109: 2161-2168.

Ried MK, Banhara A, Hwu FY, Binder A, Gust AA, Höfle C, Hückelhoven R, Nürnberger T, Parniske M. (2019) A set of Arabidopsis genes involved in the accommodation of the downy mildew pathogen Hyaloperonospora arabidopsidis. PLoS Pathog. 15(7):e1007747.

Xiao Y, Stegmann M, Han Z, DeFalco TA, Parys K, Xu L, Belkhadir Y, Zipfel C, Chai J. (2019) Mechanisms of RALF peptide perception by a heterotypic receptor complex.  Nature 572: 270–274.

Stam R, Silva-Arias GA, Tellier A (2019) Subsets of NLR genes show differential signatures of adaptation during colonisation of new habitats. New Phytol. 224: 367–379.

Metz N, Adolf B, Chaluppa N, Hückelhoven R, Hausladen H (2019) Occurrence of sdh mutations in German Alternaria solani isolates and potential impact on boscalid sensitivity in vitro, in the greenhouse and in the field. Plant Disease 103: 3065–3071.  

Sghyer H, Hess M (2019) Culture conditions influence conidial production by the barley pathogen Ramularia collo-cygni. J. Plant Dis. Prot. doi.org/10.1007/s41348-019-00226-8

Kutschera A, Dawid C, Gisch N, Schmid C, Raasch L, Gerster T, Schäffer M, Smakowska-Luzan E, Belkhadir Y, Vlot AC, Chandler CE, Schellenberger R, Schwudke D, Ernst RK, Dorey S, Hückelhoven R, Hofmann T, Ranf S (2019) Bacterial medium-chain 3-hydroxy fatty acid metabolites trigger immunity in Arabidopsis plants. Science 364(6436):178-181.

Hofer K, Hückelhoven R, Hess M (2019) Analysis of archive samples of spring and winter barley support an increase of individual Fusarium species in Bavarian barley grain over the last decades. J Plant Dis. Prot. 126: 247–254.

Geißinger C, Whitehead I, Hofer K, Heß M, Habler K, Becker T, Gastl M (2019) Influence of Fusarium avenaceum infections on barley malt: Monitoring changes in the albumin fraction of barley during the malting process. Int J Food Microbiol. 293: 7-16.

Wang S, McLellan H, Bukharova T, He Q, Murphy F, Shi J, Sun S, van Weymers P, Ren Y, Thilliez G, Wang H, Chen X, Engelhardt S, Vleeshouwers V, Gilroy EM, Whisson SC, Hein I, Wang X, Tian Z, Birch PRJ, Boevink PC (2019). Phytophthora infestans RXLR effectors act in concert at diverse subcelluar localisations to enhance host colonization. J Exp Bot. 70:343-356.

2018

Dresselhaus T, Hückelhoven R (2018) Biotic and abiotic stress responses in crop plants. Agronomy 8,267

Stegmann M (2018) EBP1: A crucial growth regulator downstream of receptor kinases across kingdoms. PLoS Biol. 16: e3000056.

Stam R, Münsterkötter M, Pophaly SD, Fokkens L, Sghyer H, Güldener U, Hückelhoven R, Hess M (2018) A new reference genome shows the one-speed genome structure of the barely pathogen Ramularia collo-cygni. Genome Biol Evol. 10:3243-3249

Rajaraman J, Douchkov D, Lück S, Hensel G, Nowara D, Pogoda M, Rutten T, Meitzel T, Brassac J, Höfle C, Hückelhoven R, Klinkenberg J, Trujillo M, Bauer E, Schmutzer T, Himmelbach A, Mascher M, Lazzari B, Stein N, Kumlehn J, Schweizer P (2018) Evolutionarily conserved partial gene duplication in the Triticeae tribe of grasses confers pathogen resistance. Genome Biol. 19:116

Kutschera A, Ranf S (2018) The multifaceted function of lipopolysaccharide in plant - bacteria interactions Biochemie 159: 93-98.

Ranf S (2018) Pattern Recognition Receptors - Versatile Genetic Tools for Engineering Broad-Spectrum Disease Resistance in Crops. Agronomy 2018, 8(8), 134

Engelhardt S, Stam R, Hückelhoven R (2018) Good Riddance? Breaking Disease Susceptibility in the Era of New Breeding Technologies. Agronomy 2018, 8(7), 114

Nottensteiner M, Zechmann B, McCollum C, Hückelhoven R (2018) A Barley powdery mildew fungus non-autonomous retrotransposon encodes a peptide that supports penetration success on barley. J. Exp. Bot. 69:3745-3758.

Beaton A, Lood C, Cunningham-Oakes E, MacFadyen A, Mullins AJ, Bestawy WE, Botelho J, Chevalier S, Coleman S, Dalzell C, Dolan SK, Faccenda A, Ghequire MGK, Higgins S, Kutschera A, Murray J, Redway M, Salih T, da Silva AC, Smith BA, Smits N, Thomson R, Woodcock S, Welch M, Cornelis P, Lavigne R, van Noort V, Tucker NP. (2018) Community-led comparative genomic and phenotypic analysis of the aquaculture pathogen Pseudomonas baetica a390T sequenced by Ion semiconductor and Nanopore technologies. FEMS Microbiol Lett. 365: doi: 10.1093/femsle/fny069.

Stam R, McDonald BA (2018) When resistance gene pyramids are not durable – the role of pathogen diversity. Mol. Plant Pathol. 19: 521-524.

Käsbauer CL, Pathuri IP, Hensel G, Kumlehn J, Hückelhoven R, Proels RK (2018) Barley ADH-1 modulates susceptibility to Bgh and is involved in chitin-induced systemic resistance. Plant Physiol. Biochem.  123: 281-287.

Hückelhoven R, Hofer K, Coleman A, Heß M (2018) Fusarium infection of malting barley has to be managed over the entire value chain. J. Plant Dis. Prot. 125:1-4

Schnepf V, Vlot AC, Kugler K, Hückelhoven R (2018) Barley susceptibility factor RACB modulates transcript levels of signalling protein genes in compatible interaction with Blumeria graminis f.sp. hordei. Mol. Plant Pathol. 19: 393-404

2017

Torres DP, Proels RK, Schempp H, Hückelhoven R (2017) Silencing of RBOHF2 causes leaf age-dependent accelerated senescence, salicylic acid accumulation and powdery mildew resistance in barley. Mol. Plant-Microbe Interact. 30: 906-918

Mondragón-Palomino M, Stam R, John-Arputharaj A, Dresselhaus T (2017) Diversification of defensins and NLRs in Arabidopsis species by different evolutionary mechanisms. BMC Evol Biol. 17(1): 255.

Jørgensen LN, Matzen N, Hansen JG, Semaskiene R, Korbas M, Danielewicz J, Glazek M, Maumene C, Rodemann B, Weigand S, Hess M, Blake J, Clark B, Kildea S, Batailles C, Ban R, Havis N, Treikale O (2017) Four azoles’ profile in the control of Septoria, yellow rust and brown rust in wheat across Europe. Crop Prot. 105: 16-27

Kutschera A,  Lamb JJ (2017) Cost-Effective Live Cell Density Determination of Liquid Cultured Microorganisms. Curr Microbiol 75: 231-236.

Höwing T,  Dann M, Hoefle C, Hückelhoven R, Gietl C (2017) Involvement of Arabidopsis thaliana endoplasmic reticulum KDEL-tailed cysteine endopeptidase 1 (AtCEP1) in powdery mildew-induced and AtCPR5-controlled cell death. PLOS One12:e 0183870

Barmeier G, Hofer K, Schmidhalter U (2017) Mid-season prediction of grain yield and protein content of spring barley cultivars using high-throughput spectral sensing. Eur. J. Agron. 90: 108-116

Ranf S (2017) Sensing of molecular patterns through cell surface immune receptors. Curr. Opin. Plant Biol. 38: 68-77.

Vaddepalli P, Fulton L, Wieland J, Wassmer K, Schaeffer M, Ranf S, Schneitz K (2017) The cell wall-localized atypical ß-1,3 glucanase ZERZAUST controls tissue morphogenesis in Arabidopsis thaliana. Development. doi: 10.1242/dev.152231.

Geißinger C, Hofer K, Habler K, Heß M, Hückelhoven R, Rychlik M, Becker T, Gastl M (2017) Fusarium species on barley malt – visual assessment as an appropriate tool for detection? Cereal Chem. 94: 659-669.

Rennberger G, Keinath AP, Hess M (2017) Correlation of trichome density and length and polyphenol fluorescence with susceptibility of five cucurbits to Didymella bryoniae. J Plant Dis. Prot. doi:10.1007/s41348-016-0050-z.

Habler K, Geissinger C, Hofer K, Schüler J, Moghari S, Hess M, Gastl M, Rychlik M (2017) Fate of Fusarium toxins during brewing.  J. Agric. Food Chem., 65: 190–198.

2016

Ranf S, Scheel D, Lee J (2016) Challenges in the identification of microbe-associated molecular patterns in plant and animal innate immunity: a case study with bacterial lipopolysaccharide. Mol Plant Pathol. 17: 1165-1169

Hückelhoven R, Seidl A (2016) PAMP-triggered immune responses in barley and susceptibility to powdery mildew. Plant Sign. Behav. 11: e1197465

Ranf S (2016) Immune sensing of lipopolysaccharide in plants and animals: Same but different. PLOS Pathog. 12: e1005596. 

Hofer K, Barmeier G, Schmidhalter U, Habler K, Rychlik M, Hückelhoven R, Hess M (2016) Effect of nitrogen fertilization on Fusarium head blight in spring barley. Crop Prot. 88: 18-27

Scheler B, Schnepf V, Galgenmüller C, Ranf S, Hückelhoven R (2016) Barley disease susceptibility factor RACB acts in epidermal cell polarity and nucleus positioning. J. Exp. Bot. 67: 3263-3275.

Hofer K, Geißinger C, König C, Gastl M, Hückelhoven R, Hess M, Coleman AD (2016) Influence of Fusarium isolates on the expression of barley genes related to plant defense and malting quality. J Cereal Sci 69: 17–24.

Weidenbach D, Esch L, Möller C, Hensel G, Kumlehn J, Höfle C, Hückelhoven R, Schaffrath U (2016) Polarized Defence Against Fungal Pathogens Is Mediated by the Jacalin-Related Lectin Domain of Modular Poaceae-Specific Proteins. Mol. Plant 9: 514-527.

Schempp H, Christof S, Mayr U, Treutter D (2016). Phenolic compounds in juices of apple cultivars and their relation to antioxidant activity. Journal of Applied Botany and Food Quality 89: 11-20.

Quentin M, Baurès I, Hoefle C, Caillaud M-C, Allasia Valérie, Panabières F, Abad P, Hückelhoven R, Keller H, Favery B (2016) The Arabidopsis MICROTUBULE-ASSOCIATED PROTEIN MAP65-3 supports infection by filamentous biotrophic pathogens by downregulating salicylic acid-dependent defences. J. Exp. Bot. 67: 1731-1743.

Linkmeyer A, Hofer K, Rychlik M, Herz M, Hausladen H, Hückelhoven R, Hess  M (2016) The influence of inoculum and climatic factors on the severity of Fusarium head blight in German spring and winter barley. Food Addit Contam. Part A. 33: 489-499. 

Habler K, Hofer K, Geißinger C, Schüler J, Hückelhoven R, Hess M, Gastl M, Rychlik M.  (2016) Fate of Fusarium Toxins during the Malting Process. J Agric Food Chem 64:1377-1384.

Reiner T, Hoefle C, Hückelhoven R (2016) A barley SKP1-like protein controls abundance of the susceptibility factor RACB and influences the interaction of barley with the barley powdery mildew fungus. Mol. Plant Pathol. 17:184-195.

2015

Hofer K, Linkmeyer A, Textor K, Hückelhoven R, Hess M (2015) MILDEW LOCUS O mutation does not affect resistance to grain infections with Fusarium spp. and Ramularia colly-cygni. Phytopathol. 105: 1214-1219.

Havis N, Clemente G, Brown J, Frei P, Jedryczka M, Kaczmarek J, Kaczmarek M, Matusinsky P, McGrann G, Pereyra S, Piotrowska M, Sghyer H, Tellier A, Hess M. (2015) Ramularia collo-cygni - an emerging pathogen of barley crops. Phytopathol. 105 :895-904.

Hemetsberger C, Mueller AN, Matei A, Herrberger C, Hensel G, Kumlehn J, Mishra B, Sharma R, Thines M, Hückelhoven R, Doehlemann G (2015) The fungal core effector Pep1 is conserved across smuts of dicots and monocots. New Phytol. 206: 1116–1126

Reiner T, Hoefle C, Huesmann C, Ménesi D, Fehér A, Hückelhoven R (2015) The Arabidopsis ROP-activated receptor-like cytoplasmic kinase RLCK VI_A3 is involved in control of basal resistance to powdery mildew and trichome branching. Plant Cell Rep. 34: 457-468

Ranf S, Gisch N, Schäffer M, Illig T, Westphal L, Knirel YA, Sánchez-Carballo PM, Zähringer U, Hückelhoven R, Lee J, Scheel D (2015) A lectn S-domain receptor kinase mediates lipopolysaccharide sensing in Arabisopsis thaliana. Nature Immunology 16: 426–433

Leiminger J, Bäßler E, Knappe C, Bahnweg G, Hausladen H (2015) Quantification of disease progression of Alternaria spp. on potato using real-time PCR. Eur. J. Plant Pathol. 141: 295-309

2014

Ranf S, Eschen-Lippold L, Fröhlich K, Westphal L, Scheel D, Lee J (2014) Microbe-associated molecular pattern-induced calcium signaling requires the receptor like cytoplsamic kinases, PBL1 and BIK1. BMC Plant Biology 14: 374

Proels RK (2014) Stable transformation of Cyanobacterium synechocystis sp. Bio-Protocol 4: e1286

Dey S, Wenig M, Langen G, Sharma S, Kugler K, Knappe C, Hause B, Bichlmeier M, Babaeizad V, Imani J, Janzik I, Stempfl T, Hückelhoven R, Kogel K-H, Mayer KFX, Vlot AC (2014) Bacteria-triggered immunity in barley is not a canonical systemic aquired resistance but is associated with WRKY and ETHYLENE RESPONSE FACTORs. Plant Physiol. 166: 2133-2151

Hok S, Allasia V, Andrio E, Naessens E, Ribes E, Panabieres F, Attard A, Ris N, Clement M, Barlet X, Marco Y, Grill E, Eichmann R, Weis C, Hückelhoven R, Ammon A, Ludwig-Müller J, Voll LM, Keller H (2014) The receptor kinase IMPAIRED OOMYCETE SUSCEPTIBILITY 1 attenuates abscisic acid responses in Arabidopsis thalina. Plant Physiol. 166, 1506-1518

Seybold H, Trempel F, Ranf S, Scheel D, Romeis T, Lee J (2014) Ca2+ signalling in plant immune response: from pattern recognition receptors to Ca2+ decoding mechanisms. New Phytol. 204, 782-790

Dörmann P, Kim H, Ott T, Schulze-Levert P, Trujillo M, Wever V, Hückelhoven R (2014) Cell-autonomous defense, re-organization and trafficking of membranes in plant-micorbe-interactions. New Phytol. 204, 815-822

Hückelhoven R (2014) The effective papilla hypothesis. New Phytol. 204, 438-440

Proels RK, Hückelhoven R (2014) Cell-wall invertases, key enzymes in the modulation of plant metabolism during defence responses. Mol. Plant. Pathol. 15, 858-864

Schwarzkopf M, Yoo YC, Hückelhoven R, Park YM, Proels RK (2014) Synechocystis phytochrome Cph2 regulates the heterotrophic metabolism and has a function in the heat and high light stress Plant Physiol. 164, 2157-2166

Weis C, Hildebrandt U, Hofmann T, Hemetsberger C, Pfeilmeier S, König C, Schwab W, Eichmann R, Hückelhoven R (2014) CYP83A1 is required for metabolic compatibility of Arabidopsis with the adapted powdery mildew fungus Erysiphe cruciferarum. New Phytologist 202, 1310-1319

Höwing T, Huesmann C, Hoefle C, Nagel M-K, Isono E, Hückelhoven R, Gietl C (2014) Endoplasmic reticulum KDEL-tailed cysteine endopeptidase 1 of Arabidopsis (AtCEP1) is involved in pathogen defense Frontiers in Plant Science (Plant Cell Biology) doi/10.3389/fpls.2014.00058 5: 58

Hof A, Zechmann B, Schwammbach D, Hückelhoven R, Doehlemann G (2014) Alternative cell death mechanisms determine epidermal resistance in incompatible barley-Ustilago interactions Mol. Plant-Microbe Interact. 27, 403-414

Hoefle C, Hückelhoven R (2014) A barley ENGULFMENT and MOTILITY domain cotaining protein modulates Rho GTPase activating protein HvMAGAP function in the barley powdery mildew interaction. Plant Mol Biol. 84: 469-478

Hu L, Gastl M, Linkmeyer A, Hess M, Rychlik M (2014) Fate of Enniatins and Beauvericin during the malting and brewing process determined by stable Isotope Dilution Assays LWT - Food and Science Technology, 56: 469-477

Proels R, Hueckelhoven R (2014) Basic protein-based methods in analysis of plant alcohol dehydrogenases. In portein an Analysis II - Methods and Applications. Edited by iConcept Press ISBN 978-1-922227-19-5

Leiminger J, Adolf B, Hausladen H (2013) Occurence of the F129L mutation in Alternaria solani populations n Germany response to QoI application and its effect on sensitivity. Plant. Pathol. 63: 640-650

2013

Oberhollenzer K, Seigner E, Eichmann R and Hückelhoven R (2013) Technique to assess gene function in Hop (Humulus lupulus L.) - powdery mildew interactions Acta Hort. (ISHS) 1010: 59-66

Hückelhoven R, Eichmann R, Weis C, Hoefle C and Pröls RK (2013) Genetic loss of susceptibility: a costly route to disease resistance? Plant Pathology 62 (Suppl.1): 56-62

Leiminger J, Auinger HJ, Wenig M, Bahnweg G, Hausladen H (2013) Genetic variability among Alternaria solani isolates from potato in Southern Germany based on RAPD-profiles. J. Plant Dis. Prot. 120: 164-172

Weis C, Hückelhoven R,  Eichmann R (2013) LIFEGUARD proteins support plant colonization by biotrophic powdery mildew fungi. J. Exp. Bot. 64: 3855-3867

Katsiarimpa A, Anzenberger F, Kalinowska K, Weis C, Ostertag M, Tsutsumi C, Wenz S, Schwechheimer C, Brunner F, Hückelhoven R, Isono E (2013) AMSH1 and ESCRT-III subunit VPS2.1 are required for autophagic degradation in Arabidopsis thaliana. The Plant Cell 25: 2236-2252

Linkmeyer A, Götz M, Hu L, Asam S, Rychlik M, Hausladen H, Hess M, Hückelhoven R (2013) Assessment and Introduction of quantiative resistance to Fusarium head blight in elite spring barley. Phytopathology 103: 1252-1259

Weis C, Pfeilmeier S, Glawischnig E, Isono E, Pachl F, Hahne H, Kuster B, Eichmann R, Hückelhoven R (2013) Co-immunoprecipitation-based identification of putative BAX-INHIBITOR-1- interacting proteins involved in cell death regulation and plant - powdery mildew interactions. Mol. Plant Pathol. 14: 791-802

Engelsdorf I,Horst RJ, Pröls R, Pröschel M., Dietz F, Hückelhoven R, Voll LM (2013) Reduced carobohydrate availabiltiy enhances susceptibility of Arabidopsis towards Colletotrichum higginsianum. Plant Physiol 162: 225-238

Ostertag Maya, Stammler Johanna, Douchkov Dimitar, Eichmann Ruth, Ralph Hückelhoven (2013) The conserved oligomeric Golgi complex is involved in penetration resistance of barley to the barley powdery mildew fungus.Mol. Plant. Pathol. 14:230-240

Hückelhoven R, Hoefle C, Proels R, Eichmann R (2013) The powdery mildew fungus Blumeria graminis reprograms barley for triggering susceptibility. Nova Acta Leopoldina 114 (391): 230-240

2012

Reitz MU, Bissue JK, Zocher K, Attard A, Hückelhoven R, Becker K, Imani J, Eichmann R, Schäfer P (2012) The subcellular localization of Tubby-like proteins and participation in stress signaling and root colonization by the mutualist Piriformospora indica. Plant Physiol. 160: 349-364 

Huesmann C, Reiner T, Hoefle C, Preuss J, Jurca ME, Domoki M, Fehér A, Hückelhoven R (2012) Barley ROP binding kinase 1 is involved in microtubule organization and in basal penetration resistance to the barley powdery mildew fungus. Plant Physiol. 159: 311-320 

Leiminger JH, Hausladen H (2012) Early blight control in potatoes using disease orientated threshold values. Plant Disease 96:124-130 

2011

Hückelhoven R, Panstruga R (2011) Cell biology of the plant–powdery mildew interaction. Current Opinion in Plant Biology 14: 738-746

Huesmann C, Hoefle C, Hückelhoven R (2011) ROPGAPs of Arabidopsis limit susceptibility to powdery mildew. Plant Signaling & Behavior 6: 1691-1694

Hoefle C, Huesmann C, Schultheiss H, Börnke F, Hensel G, Kumlehn J, Hückelhoven R (2011) A barley ROP GTPase ACTIVATING PROTEIN associates with microtubules and regulates entry of the barley powdery mildew fungus into leaf epidermal cells. The Plant Cell 23: 2422-2439

Proels RK, Westermeier W, Hückelhoven R (2011): Infection of barley with the parasitic fungus Blumeria graminis f.sp. hordei results in the induction of HvADH1 and HvADH2. Plant Signaling & Behavior 6: 1584-1587

Pathuri IP, Reitberger IE, Hückelhoven R, Proels RK (2011) Alcohol dehydrogenase 1 of barley modulates susceptibility to the parasitic fungus Blumeria graminis f.sp. hordei. J Exp Bot. 62:3449-3457

Bischof M, Eichmann R, Hückelhoven R (2011) Pathogenesis-associated transcriptional patterns in Triticeae. J Plant Physiol. 168: 9–19

2010

Mucha E, Hoefle C, Hückelhoven R, Berken A (2010) RIP3 and AtKinesin-13A - A novel interaction linking Rho proteins of plants to microtubules. Eur. J. Cell Biol. 89: 906-916

Schempp H, Vogel S, Hückelhoven R, Heilmann J (2010) Re-evaluation of superoxide scavenging capacity of xanthohumol. Free Rad. Res. 44 (12): 1435-1444

Eichmann R, Bischof M, Weis C, Jane Shaw, Lacomme C, Schweizer P, Dimitar Duchkov, Hensel G, Kumlehn G, Hückelhoven R (2010) BAX INHIBITOR-1 is required for full susceptibility of barley to the barley powdery mildew fungus. Mol Plant-Microbe Interact 23: 1217-1227

Proels RK, Oberhollenzer K, Pathuri IP, Hensel G, Kumlehn J, Hückelhoven R (2010) RBOHF2 of barley is required for normal development of basal penetration resistance to the parasitic fungus Blumeria graminis f.sp. hordei. Mol Plant-Microbe Interact 23: 1143-1150

Lorek J, Panstruga R, Hückelhoven R (2010) The role of seven-transmembrane domain MLO proteins, heterotrimeric G-proteins, and monomeric rac/rops in plant defense. In: Integrated G Proteins Signaling in Plants, Signaling and Communication in Plants, S. Yalovsky, F. Baluska & A. Jones (eds.), Heidelberg, Dordrecht, London, New York, pp. 197-220

2009

Pathuri PI, Imani J, Babaeizad V, Eichmann R, Hückelhoven R (2009) Ectopic expression of barley constitutively activated ROPs supports susceptibility to powdery mildew and bacterial wildfire in tobacco. Eur. J. Plant Pathol. 125: 317-327

Möller K, Dilger M, Habermeyer J, Zinkernagel V, Flier WG, Hausladen H (2009) Population studies on Phytophthora infestans on potatoes and tomatoes in southern Germany Eur J Plant Pathol 124: 659-672

Hoefle C, Loehrer M, Schaffrath U, Frank M, Schultheiss H, Hückelhoven R (2009) Transgenic suppression of cell death limits penetration success of the soybean rust fungus Phakopsora pachyrhizi into epidermal cells of barley. Phytopathology 99: 220-226

Pathuri PI, Eichmann R, Hückelhoven R (2009) Plant small monomeric G-proteins (RAC/ROPs) of barley are common elements of susceptibility to fungal leaf pathogens, cell expansion and stomata development. Plant Signaling & Behavior. 4: 109-110

Babaeizad V, Imani J, Kogel K-H, Eichmann R, Hückelhoven R (2009) Over-expression of the cell death regulator BAX inhibitor-1 in barley confers reduced or enhanced susceptibility to distinct fungal pathogens. Theoret. Appl. Genet. 118: 455-463

2008

Hoefle C, Hückelhoven R (2008) Enemy at the gates – traffic at the plant cell pathogen interface. Cell Microbiol. 10: 2400-2407

Pathuri PI, Hensel G, Kumlehn J, Eichmann R, Hückelhoven R (2008) Constitutively activated barley ROPs modulate epidermal cell size, defense reactions and interactions with fungal leaf pathogens. Plant Cell Rep. 1877-1887

Schultheiss H, Preuss J, Pircher T, Eichmann R, Hückelhoven R (2008) Barley RIC171 interacts with RACB in planta and supports entry of the powdery mildew fungus. Cell. Microbiol. 10: 1815–1826

Felle HH, Herrmann A, Schafer P, Hückelhoven R, Kogel KH (2008) Interactive signal transfer between host and pathogen during successful infection of barley leaves by Blumeria graminis and Bipolaris sorokiniana. J Plant Physiol. 165: 52-59

Eichmann R, Hückelhoven R (2008) Accommodation of powdery mildew fungi in intact plant cells. J Plant Physiol 165: 5-18

2007

Hückelhoven R (2007) Transport and secretion in plant-microbe interactions. Curr Opin Plant Biol 10: 573-579

An Q, van Bel AJE, Hückelhoven R (2007) Do plant cells secrete exosomes derived from multivesicular bodies? Plant Signaling & Behavior 2: 4-7

Hückelhoven R (2007) Cell Wall-Associated Mechanisms of Disease Resistance and Susceptibility. Ann Rev Phytopathol 45: 101-127

2006

Deshmukh S, Hückelhoven R, Schäfer P, Imani J, Sharma M, Weiss M, Waller F, Kogel K-H (2006) The root endophytic fungus Piriformospora indica requires host cell death for proliferation during mutualistic symbiosis with barley. Proc Natl Acad Sci USA 103: 18450–18457

Trujillo M, Altschmied L, Schweizer P, Kogel K-H, Hückelhoven R (2006) Respiratory Burst Oxidase Homologue A of barley contributes to penetration by the powdery mildew fungus Blumeria graminis f.sp. hordei. J Exp Bot. 57: 3781–3791

Eichmann R, Dechert C, Kogel K-H, Hückelhoven R (2006) Transient over-expression of barley BAX Inhibitor-1 weakens oxidative defence and MLA12-mediated resistance to Blumeria graminis f.sp. hordei. Mol Plant Pathol. 7: 543–552

An Q, Ehlers K, Kogel K-H, van Bel AJE, Hückelhoven R (2006) Multivesicular compartments proliferate in susceptible and resistant MLA12-barley leaves in response to infection by the biotrophic powdery mildew fungus. New Phytologist 172: 563–576

Imani J, Baltruschat H, Stein E, Jia G, Vogelsberg J, Kogel K-H, Hückelhoven R (2006) Expression of barley BAX Inhibitor-1 in carrots confers resistance to Botrytis cinerea. Mol Plant Pathol 7: 279-284

Kogel KH, Franken P, Hückelhoven R (2006) Endophyte or parasite - what decides? Curr Opin Plant Biol 9: 358–363

Opalski KS, Tresch S, Kogel KH, Grossmann K, Kohle H, Hückelhoven R (2006) Metrafenone: studies on the mode of action of a novel cereal powdery mildew fungicide. Pest Manag Sci. 62: 393-401

An Q, Hückelhoven R, Kogel K-H, van Bel AJE (2006) Multivesicular bodies participate in a cell wall-associated defence response in barley leaves attacked by the pathogenic powdery mildew fungus. Cell Microbiol 8:1009-1019

Eichmann R, Biemelt S, Schafer P, Scholz U, Jansen C, Felk A, Schafer W, Langen G, Sonnewald U, Kogel KH, Huckelhoven R (2006) Macroarray expression analysis of barley susceptibility and nonhost resistance to Blumeria graminis. J Plant Physiol 163: 657-670

Schempp H, Weiser D, Kelber O, Elstner EF. (2006) Radical scavenging and anti-inflammatory properties of STW 5 (Iberogast) and its components. Phytomedicine 13 Suppl 5: 36-44

Hecht D, Zinkernagel V (2006) Epidemiological studies of cherry leaf scorch (Gnomonia erythrostoma).  J.Plant Disease and Protection 113: 68-73

2005

Hückelhoven R (2005) Powdery mildew susceptibility and biotrophic infection strategies FEMS Microbiol Lett 245: 9-17

Felle HH, Herrmann A, Hückelhoven R, Kogel K-H (2005) Root-to-shoot signalling: apoplastic alkalinization, a general tress response and defence factor in barley (Hordeum vulgare). Protoplasma 227: 17-24

Waller F, Baltruschat H, Achatz B, József Fodor, Becker K, Fischer M, Heier T, Hückelhoven R, Neumann C, von Wettstein D, Franken P, Kogel K-H (2005) The endophytic fungus Piriformospora indica reprograms barley to salt-stress tolerance, disease resistance, and higher yield. Proc Natl Acad Sci USA 102:13386-13391

Schultheiss H, Hensel G, Imani J, Broeders S, Kumlehn J, Kogel K-H, Sonnewald U, Hückelhoven R (2005) Ectopic expression of constitutively activated RACB in barley enhances susceptibility to powdery mildew and abiotic stress. Plant Physiol 139: 353-362

Ibeagha AE, Hückelhoven R, Schäfer P, Singh DP, Kogel K-H (2005) Model wheat genotypes as tools to discover effective defence mechanisms against the hemibiotrophic fungus Bipolaris sorokiniana (teleomorph: Cochliobolus sativus). Phytopathol 95:528-532

Opalski KS, Schultheiss H, Kogel K-H, Hückelhoven R (2005) The receptor-like MLO protein and the RAC/ROP family G-protein RACB modulate actin reorganization in barley attacked by the biotrophic powdery mildew fungus Blumeria graminis f.sp. hordei. Plant J 41: 291-303

Janisch KM, Milde J, Schempp H, Elstner EF. (2005) Vitamin C, vitamin E and flavonoids. Dev Ophthalmol.; 38:59-69. Review.

2004

Hückelhoven R (2004) BAX Inhibitor-1, an ancient cell death suppressor in animals and plants with prokaryotic relatives. Apoptosis 9: 299-307

Patent (2004) WO 2004009820: Methods for obtaining the pathogenic resistance in plants. Erfinder: R. Hückelhoven, K-H. Kogel, M. Trujillo

Patent (2004) WO 2004081217: Methods for increasing resistance against stress factors in plants. Erfinder: Frank M. , R. Hückelhoven, K-H. Kogel

Eichmann R, Schultheiss H, Kogel K-H, Hückelhoven R (2004) The barley apoptosis suppressor homologue Bax Inhibitor-1 compromises nonhost penetration resistance of barley to the inappropriate pathogen Blumeria graminis f.sp. tritici. Mol Plant-Microbe Interact 17: 484-490

Trujillo M, Troeger M, Niks R, Kogel K-H, Hückelhoven R (2004) Mechanistic and genetic overlap of barley host and non-host resistance to Blumeria graminis. Mol Plant Pathol 5: 389-396

Schäfer P, Hückelhoven R, Kogel K-H (2004) The white barley mutant albostrians shows a supersusceptible but symptomless interaction phenotype with the hemibiotrophic fungus Bipolaris sorokiniana (Teleomorph: Cochliobolus sativus). Mol Plant-Microbe Interact 17: 366-373

Jain SK, Langen G, Börner T, Hess W, Hückelhoven R, Kogel K-H (2004) The barley albino mutant Albostrians shows enhanced resistance to the biotroph Blumeria graminis f.sp. hordei. Mol Plant-Microbe Interact 17: 374-382

Trujillo M, Kogel K-H, Hückelhoven R (2004) Superoxide and hydrogen peroxide play different roles in non-host interactions of cereals and inappropriate formae speciales of Blumeria graminis. Mol Plant-Microbe Interact 17: 304-312

Felle HH, Herrmann A, Hanstein S, Hückelhoven R, Kogel K-H (2004) Apoplastic pH signalling in barley leaves attacked by the powdery mildew fungus Blumeria graminis f.sp. hordei. Mol Plant-Microbe Interact 17: 118-123

Janisch K, Schempp H. (2004) Evaluation of the oxidative burst in suspension cell culture of Phaseolus vulgaris. Z Naturforsch [C]. 59(11-12): 849-855

Giese T, McGrath MS, Stumm S, Schempp H, Elstner E, Meuer SC. (2004) Differential effects on innate versus adaptive immune responses by WF10. Cell Immunol. 229(2)149-58

Schempp H, Hippeli S, Weiser D, Kelber O, Elstner EF. (2004) Comparison of the inhibition of myeloperoxidase-catalyzed hypochlorite formation in vitro and in whole blood by different plant extracts contained in a phytopharmacon treating functional dyspepsia. Drug 'Research 54(7): 389-395.

Heiser I, Hess M, Schmidtke KU, Vogler U, Miethbauer S, Liebermann B (2004) Fatty acid peroxidation by rubellin B, C and D, phytotoxins produced by Ramularia collo-cygni (Sutton et Waller). Physiological and Molecular Plant Pathology 64 (3), 135-143

2003

Hückelhoven R, Dechert C, Kogel K-H (2003) Overexpression of barley BAX inhibitor 1 induces breakdown of mlo-mediated penetration resistance to Blumeria graminis. Proc Natl Acad Sci USA 100: 5555-5560

Collins NC, Thordal-Christensen H, Lipka V, Bau S, Kombrink E, Qiu J-L, Hückelhoven R, Stein M, Freialdenhoven A, Somerville SC, Schulze-Lefert P (2003) SNARE-protein-mediated disease resistance at the plant cell wall. Nature 425: 973-977

Schultheiss H, Dechert C, Kogel K-H, Hückelhoven R (2003) Functional analysis of barley RAC/ROP G-protein family embers in susceptibility to the powdery mildew fungus. Plant J 36: 589-601

Schultheiss H, Dechert C, Király L, Fodor J, Michel K, Kogel K-H, Hückelhoven R (2003) Functional assessment of the pathogenesis-related protein PR-1b in barley. Plant Science 165: 1275–1280

Patent (2003) WO 03020939: Novel nucleic acid sequences and their use in methods for achieving pathogen resistance in plants. Erfinder: M. Frank; R. Hückelhoven, K-H. Kogel, H. Schultheiss

Hückelhoven R, Kogel K-H (2003) Reactive oxygen intermediates in plant-microbe interactions: Who is who in powdery mildew resistance? Planta 216: 891–902

Schempp H, Toth A, Weiser D, Elstner EF. (2003) Antioxidative properties of Iberis amara extracts in biochemical model reactions. Drug Research 53(8): 568-577.

2002

Schultheiss H, Dechert C, Kogel K-H, Hückelhoven R (2002) A Small GTP-binding host protein is required for entry of powdery mildew fungus into epidermal cells of barley. Plant Physiol 128: 1447-1454

Kumar J, Schäfer P, Hückelhoven R, Langen G, Baltruschat H, Stein E, Nagarajan S, Kogel K-H (2002) Bipolaris sorokiniana, a cereal pathogen of global concern: cytological and molecular approaches towards better control. Review, Mol Plant Pathol 3: 185-195

2001

Hückelhoven R, Dechert C, Trujillo M, Kogel K-H (2001) Differential expression of putative cell death regulator genes in near-isogenic, resistant and susceptible barley lines inoculated with the powdery mildew fungus. Plant Mol Biol 47: 739-748

Hückelhoven R, Dechert C, Kogel K-H (2001) Non-host resistance of barley is associated with a hydrogen peroxide burst at sites of attempted penetration by wheat powdery mildew fungus. Mol Plant Pathol 2: 199-205

Kumar J, Hückelhoven R, Beckhove U, Nagarajan S, Kogel K-H (2001) A compromised Mlo pathway affects the response of barley to the necrotrophic fungus Bipolaris sorokiniana (teleomorph: Cochliobolus sativus) and its toxins. Phytopathol 91: 127-133

Schempp H, Reim M, Dornisch K, Elstner EF. (2001) Chlorite-hemoprotein interaction as key role for the pharmacological activity of the chlorite-based drug WF10. Drug Research 51(7): 554-562.

2000

Hückelhoven R, Trujillo M, Kogel K-H (2000) Mutations in Ror1 and Ror2 genes cause modification of hydrogen peroxide accumulation in mlo-barley under attack from the powdery mildew fungus. Mol Plant Pathol 1: 287-292

Hückelhoven R, Fodor J, Trujillo M and Kogel K-H (2000) Barley Mla- and Rar-mutants compromised in the hypersensitive cell death response against Blumeria graminis f.sp. hordei are modified in their ability to accumulate reactive oxygen intermediates at sites of fungal invasion. Planta 212: 16-24

Hückelhoven R, Kogel K-H (2000) Association of hydrogen peroxide accumulation with expression of PR-1 during defence of barley against the powdery mildew fungus. Acta Phytopathologica et Entomologica Hungarica 35: 231-238

Denke A, Schempp H, Weiser D, Elstner EF. (2000) Biochemical activities of extracts from Hypericum perforatum L. 5th communication: dopamine-beta-hydroxylase-product quantification by HPLC and inhibition by hypericins and flavonoids. Drug Research 50(5): 415-419.

Schempp H, Weiser D, Elstner EF. (2000) Biochemical model reactions indicative of inflammatory processes. Activities of extracts from Fraxinus excelsior and Populus tremula. Drug Research 50(4): 362-372.

1999

Hückelhoven R, Fodor J, Preis, C, Kogel K-H (1999) Hypersensitive cell death and papilla formation in barley attacked by the powdery mildew fungus are associated with H2O2 but not with salicylic acid accumulation. Plant Physiol 119: 1251-1260

Kogel K-H, Hückelhoven R (1999) Superoxide generation in chemically activated resistance of barley in response to powdery mildew inoculation. J Phytopathol 147: 1-4

Schempp H, Albrecht-Goepfert E, Elstner EF. (1999) Detection of the production of reactive oxygen species by neutrophils in whole blood: modulation by adamantanes and triggering by Fe(3+)-ions. Z Naturforsch [C]. 54(7-8)562-8

Denke A, Schempp H, Mann E, Schneider W, Elstner EF. (1999) Biochemical activities of extracts from Hypericum perforatum L. 4th Communication: influence of different cultivation methods. Drug Research 49(2): 120-125.

Schempp H, Denke A, Mann E, Schneider W, Elstner EF. (1999) Biochemical activities of extracts from Hypericum perforatum L. 3rd Communication: modulation of peroxidase activity as a simple method for standardization. Drug Research 49(2): 115-119.

1998

Hückelhoven R, Kogel K-H (1998) Tissue-specific superoxide generation at interaction sites in resistant and susceptible near-isogenic barley lines attacked by the powdery mildew fungus (Erysiphe graminis f.sp. hordei). Mol Plant-Microbe Interact 11: 292-300

Albrecht-Goepfert E, Schempp H, Elstner EF. (1998) Modulation of the production of reactive oxygen species by pre-activated neutrophils by aminoadamantane derivatives. Biochem Pharmacol. 56(1): 141-152.

1997

Hückelhoven R, Schuphan I, Thiede B, Schmidt B (1997) Biotransformation of pyrene by cell cultures of soybean (Glycine max L.), wheat (Triticum aestivum L.), jimsonweed (Datura stramonium L.), and purple foxglove (Digitalis purpurea L.). J Agric Food Chem 45: 263-269

1996 and older

von Kruedener S, Schempp H, Elstner EF. (1995) Gas chromatographic differentiation between myeloperoxidase activity and Fenton-type oxidants. Free Rad. Biol. Med. 19(2): 141-146.

Schempp H, Ulrich H, Elstner EF. (1994) Stereospecific reduction of R(+)-thioctic acid by porcine heart lipoamide dehydrogenase/diaphorase. Z Naturforsch [C]. 49(9-10): 691-692.